Damage tolerance analysis consists of three parts such as the calculation of the residual strength diagram to obtain the permissible crack size, calculation of the crack growth curve, and calculation of the inspection interval. This article discusses the aspects of obtaining material property data and geometry factors to analyze any fracture or crack growth problem. It describes the integration of crack growth rates in terms of constant-amplitude loading and cycle-by-cycle counting with variable-amplitude loading. The article concludes with information on the classification of sources of error in damage tolerance analysis.