This chapter describes the conditions under which copper-base alloys are susceptible to stress-corrosion cracking (SCC) and some of the environmental factors, such as temperature, pH, and corrosion potential, that influence crack growth and time to failure. It explains that, although most of the literature has been concerned with copper zinc alloys in ammoniacal solutions, there are a number of alloy-environment combinations where SCC has been observed. The chapter discusses several of these cases and the effect of various application parameters, including composition, microstructure, heat treatment, cold working, and stress intensity. It also provides information on stress-corrosion testing, mitigation techniques, and basic cracking mechanisms.