Abstract
This study shows that the osteogenic abilities of calcium silicate based coatings can be improved through nanotopographical surface modifications and the addition of bioactive trace elements. CaSiO3 powders were deposited on titanium substrates by atmospheric plasma spraying and the topography and composition of the resulting coatings were modified by hydrothermal treatments in deionized water and in aqueous solutions of Sr(NO3)2. Bone marrow stem cells were cultured on treated and untreated coatings. The cells spread further on treated surfaces and were found to be relatively larger in size than the cells on untreated surfaces. Calcium silicate coatings treated in the strontium-containing solution showed the best overall improvement in terms of bone cell growth and differentiation.
