Due to advanced technical, economic and environmental reasons, radial shaft and hydraulic rod seals demand new wear resistant counterface materials. Thermal spraying offers one alternative to common hardening and hard plating technologies. Applying corrosion resistant ceramic coatings by Thermal Spraying leads to new applications in sealing systems. The combination with PTFE-compound sealing materials can be used with aqueous, non-lubricating and corrosive fluids. The authors have carried out extensive research on how the coating material and the surface structure of the coating effect hydraulic rod and radial shaft sealing systems. The presented results show that the influence of the coating on the sealing is critical for the performance of both standard and new custom sealing systems.