Mechanical properties of water stabilized plasma spray-formed Al2O3-13wt%TiO2 have been investigated by using indentation techniques and a four-point bend test. Young's modulus was determined by four point bend, nano- and Knoop indentation tests. Modulus of rupture was measured by the four-point bend test. The anisotropic behavior as well as the reduced Young's modulus and strength of thermal spray deposits are extensively investigated and can be related to the unique microstructure; i.e., the spheroidal shape of pores, cracks and splats as well as inter-lamellar boundaries. The heat treatment substantially enhanced the mechanical properties and the microstructure becomes more homogeneous and isotropic; that is, the deposits lose their unique nature and become more similar to bulk materials.