The development of High Velocity Oxy-Fuel (HVOF) process shows a clear trend toward the design of new gun in which high pressure and large power are expected in order to obtain a stable flame and a high powder feed rate for industrial applications. In this work, a new HVOF gun, AMT-200, was used to prepare NiCrAlY and WC-Co-Cr coatings. To optimise the spraying parameters, i.e., flux rates of oxygen and fuel gas and spraying distance, the on line control system AMT Spraying Xplorer was used. The results show that the spraying parameters play significant roles on the properties of NiCrAlY coatings. Employing optimized parameters, a dense NiCrAlY coating, with a high coating/substrate bonding strength and low oxygen content, could be obtained by this system. Moreover, thermal treatment could reduce significantly the coating porosity and increase greatly coating/substrate bonding strength. The preliminary tests on WC-Co-Cr coating indicate that dense cermet based coatings could be deposited with this system.