Titanium dioxide coating can be deposited by many processes such as thermal spray, Sol-Gel, vapor deposition, and so on. Among those coating deposition methods, thermal spray process is characterized by rapid formation of coatings easily and flexibly compared with other coating depositing processes. It is reported that nano-structured materials such as aluminum oxide, manganese(III) oxide, and zirconium dioxide could be produced by thermal spraying process with liquid feedstocks. With the process using liquid feedstocks, it was reported previously that nano-structured anatase titanium dioxide can be synthesized and the deposit mainly consist of anatase phase. In this paper, the effects of spray parameters on the grain size and phase structure of titanium dioxide deposits are systematically studied using liquid flame spraying system with butyl titanate as a liquid precursor. Paper includes a German-language abstract.