With increasing complexity involved in advance node semiconductor process development, dependability on parametric test structures has also increased significantly. Test structures play a predominant role throughout the entire development cycle of a product. It becomes very important to understand the root cause of failures at fastest pace to take necessary corrective actions. The use of ultra low K dielectrics for back end of line wafer build for advanced nodes created significant constraints on conventional beam imaging methods for fault isolation. This paper provides a streamlined process flow for root cause identification on shorts on advanced 20 nm and sub-20 nm technologies. Three unique cases are presented to demonstrate three typical situations identified in the process flow. They are blown capacitors, gate leakage, and resistance ladder short isolation.