As the technology keeps scaling down and IC design becomes more and more complex, failure analysis becomes much more challenging, especially for static fault isolation. For semiconductor foundry FA, it will become even more challenging due to lack of enough information. Static fault isolation is the major global fault isolation methodology in foundry FA and it is difficult to access and trigger the failing signal detected by scan and BIST test, which is widely applied in modern IC design. Because, in most of the time, the normal two pin bias (Vdd and Vss) can only get the comparable IV result between bad unit and the reference unit for function related fail. There are two possibilities from reverse engineering perspective. Firstly, the defect location may not be accessed by the DC bias. Secondly, even if the defect can be accessed, but the defect induced current or voltage change is too small to be differentiated from the overall signal. So it will be concealed in the overall current. However, it is still possible for us to do global fault isolation for the second situation. In this paper, a unit with Iddoff failure was analyzed. Although, no significant IV difference was observed between failed and reference units, a distinct Photon Emission (EMMI) spot was successfully observed in the failed unit. Layout analysis and process analysis on this EMMI spot further confirmed the reality of the emission spot.