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Series: ASM Handbook
Volume: 2
Publisher: ASM International
Published: 01 January 1990
DOI: 10.31399/asm.hb.v02.a0001119
EISBN: 978-1-62708-162-7
...Abstract Abstract Metal contamination of the environment reflects both natural sources and industrial activity, affecting human health. This article begins with a discussion on the level of metal exposure resulting in toxicological effects, the factors influencing toxicity of metals...
Abstract
Metal contamination of the environment reflects both natural sources and industrial activity, affecting human health. This article begins with a discussion on the level of metal exposure resulting in toxicological effects, the factors influencing toxicity of metals, and carcinogenicity of metal compounds. It discusses some commonly used chelating agents for treating metal intoxication, and clinical effectiveness in treating poisoning by different metals. The metals discussed are grouped into four categories: (1) major toxic metals with multiple effects, including arsenic, beryllium, cadmium, chromium, lead, mercury, and nickel; (2) essential metals with potential for toxicity, including cobalt, copper, iron, manganese, molybdenum, selenium, and zinc; (3) metals with toxicity related to medical therapy, including aluminum, bismuth, gallium, gold, lithium, and platinum; and (4) minor toxic metals, including antimony, barium, indium, magnesium, silver, tellurium, thallium, tin, titanium, uranium, and vanadium. The main factors included in the discussion are their disposition, toxicity, biological factors and treatment.
Image
Published: 01 August 2013
Fig. 100 Molecular structures of toxic polyaromatic hydrocarbons. Source: Ref 251
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Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005665
EISBN: 978-1-62708-198-6
... aspects of ion toxicity. These include ion concentration and accumulation in organisms, reactive oxygen species and oxidative stress, and carcinogenicity stimulated by the corrosion process and toxic ions release. biocompatibility carcinogenicity corrosion corrosion resistance immunogenicity...
Abstract
This article describes the corrosion resistance and ion release from main transition metallic bearings used as medical devices. It discusses the main issues associated with the in vivo presence of ions and their biocompatibility during the exposure of patients to different aspects of ion toxicity. These include ion concentration and accumulation in organisms, reactive oxygen species and oxidative stress, and carcinogenicity stimulated by the corrosion process and toxic ions release.
Series: ASM Handbook
Volume: 18
Publisher: ASM International
Published: 31 December 2017
DOI: 10.31399/asm.hb.v18.a0006374
EISBN: 978-1-62708-192-4
... caused by brake pads. The article concludes with information on physical and chemical testing of brakes and toxicity of brake formulation and regulations. aircraft brake linings aircraft brakes automotive brakes brake pads cast iron casting chemical testing disk brakes drum brakes friction...
Abstract
This article focuses on friction and wear of automotive and aircraft brakes. It provides a comparison of friction and wear behaviors, frictional characteristics, and frictional performance of the friction materials. The article describes the components of brake friction materials and the classifications of brake lining materials. It discusses the effect of formulation compositions and manufacturing processes and the effect of braking operation conditions. The article provides information on aircraft brake linings, which operate under a wide range of kinetic energy conditions. The morphology effect of graphite on automotive brake drum and disk is explained. The article also describes the characteristics of specific wear rates for both normal and local cast iron in automotive brake drums and disk rotors. It provides information on noises, vibrations, and harshness caused by brake pads. The article concludes with information on physical and chemical testing of brakes and toxicity of brake formulation and regulations.
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005666
EISBN: 978-1-62708-198-6
..., namely, neuropathic effects, hypersensitivity effects, carcinogenicity, and general toxicity. biologic aspects carcinogenicity cobalt alloys debris-induced systemic effects hypersensitivity implant debris local inflammation local osteolysis neuoropathic effects orthopedic implants...
Abstract
Implant debris is known to cause local inflammation, local osteolysis, and, in some cases, local and systemic hypersensitivity. The debris can be stainless steel, cobalt alloy, and titanium alloy, and soluble debris obtained due to wear from all orthopedic implants. This article addresses the biologic aspects of implant debris, both locally and systemically. It describes debris-induced local effects, particle-induced proinflammatory responses, and debris-induced systemic effects. The article concludes with a discussion on the four systemic effects of implant debris, namely, neuropathic effects, hypersensitivity effects, carcinogenicity, and general toxicity.
Series: ASM Handbook
Volume: 2
Publisher: ASM International
Published: 01 January 1990
DOI: 10.31399/asm.hb.v02.a0001085
EISBN: 978-1-62708-162-7
... and precautions associated with processing depleted uranium and methods to control mild radioactivity, chemical toxicity, and pyrophoricity. It also describes the classification and heat treatment of uranium and uranium alloys. Furthermore, the article provides graphical representation of the effect of alloy...
Abstract
Uranium is a moderately strong and ductile metal that can be cast, formed, and welded by a variety of standard methods. This article presents an overview of the processing and properties of uranium and uranium alloys with a brief overview of the principal hazards and precautions associated with processing depleted uranium and methods to control mild radioactivity, chemical toxicity, and pyrophoricity. It also describes the classification and heat treatment of uranium and uranium alloys. Furthermore, the article provides graphical representation of the effect of alloy composition, cooling rate, and aging temperature on microstructure, crystal structure, and mechanical properties of uranium and uranium alloys.
Series: ASM Handbook
Volume: 4B
Publisher: ASM International
Published: 30 September 2014
DOI: 10.31399/asm.hb.v04b.a0005926
EISBN: 978-1-62708-166-5
..., explosion, toxicity, and asphyxiation. The article reviews the fundamentals of principal gases and vapors. It describes how the evaluation of the atmospheric requirements of heat treating furnaces is influenced by factors such as cost of operation and capital investment. atmosphere furnaces...
Abstract
This article provides a detailed discussion on the types of furnace atmospheres required for heat treating. These include generated exothermic-based atmospheres, generated endothermic-based atmospheres, generated exothermic-endothermic-based atmospheres, generated dissociated-ammonia-based atmospheres, industrial gas nitrogen-base atmospheres, argon atmospheres, and hydrogen atmospheres. Atmospheres for backfilling, partial pressure operation, and quenching in vacuum are also discussed. Furnace atmospheres constitute four major groups of safety hazards in heat treating: fire, explosion, toxicity, and asphyxiation. The article reviews the fundamentals of principal gases and vapors. It describes how the evaluation of the atmospheric requirements of heat treating furnaces is influenced by factors such as cost of operation and capital investment.
Series: ASM Handbook
Volume: 14B
Publisher: ASM International
Published: 01 January 2006
DOI: 10.31399/asm.hb.v14b.a0005159
EISBN: 978-1-62708-186-3
... the discussions are relevant to metal-forming operations in general. The article also deals with lubricant selection as influenced by the metal to be formed and particular sheet-metal forming operations. The article also discusses some aspects of microbiology and toxicity in lubricants. dies lubricant...
Abstract
This article provides an overview of the interfacial interactions with a lubricant film between a die and a metal, lubricant mechanisms, chemistry, qualification testing, application methods, and property test methods. It focuses on sheet metal-forming operations, although the discussions are relevant to metal-forming operations in general. The article also deals with lubricant selection as influenced by the metal to be formed and particular sheet-metal forming operations. The article also discusses some aspects of microbiology and toxicity in lubricants.
Book: Powder Metallurgy
Series: ASM Handbook
Volume: 7
Publisher: ASM International
Published: 30 September 2015
DOI: 10.31399/asm.hb.v07.a0006137
EISBN: 978-1-62708-175-7
... with producing and using common sintering atmosphere gases are explosion, fire, toxicity, and asphyxiation. atmosphere supply systems inspection maintenance safety and environmental concerns sintering atmosphere generators sintering atmospheres SINTERING ATMOSPHERES (endothermic gas, exothermic...
Abstract
This article discusses the requirements for safe design, installation, operation, inspection, testing, and maintenance of sintering atmosphere generators and atmosphere supply systems for both personal and environment safety. The four intrinsic dangers associated with producing and using common sintering atmosphere gases are explosion, fire, toxicity, and asphyxiation.
Series: ASM Handbook
Volume: 13A
Publisher: ASM International
Published: 01 January 2003
DOI: 10.31399/asm.hb.v13a.a0003691
EISBN: 978-1-62708-182-5
... response to the enacted as well as proposed legislation of limiting the use of potentially harmful or toxic raw materials or surface preparation and/or application techniques. The article summarizes the existing federal regulations affecting the coatings industry categorized according to the requirements...
Abstract
This article presents an overview of the different types of coating and lining materials available. It provides information on the various means of surface preparation and the equipment and techniques of coating application. The article discusses the coatings industry's response to the enacted as well as proposed legislation of limiting the use of potentially harmful or toxic raw materials or surface preparation and/or application techniques. The article summarizes the existing federal regulations affecting the coatings industry categorized according to the requirements of the Environmental Protection Agency and the Occupational Safety and Health Administration as well as the corresponding Code of Federal Regulation numbers.
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005660
EISBN: 978-1-62708-198-6
...Abstract Abstract The biocompatibility of a material relates to its immunological response, toxicity profile, and ability to integrate with surrounding tissue without undesirable local or systemic effects on a patient. This article underscores the transformation of the medical device design...
Abstract
The biocompatibility of a material relates to its immunological response, toxicity profile, and ability to integrate with surrounding tissue without undesirable local or systemic effects on a patient. This article underscores the transformation of the medical device design ecosystem engaged as an integral part of the device ecosystem. It discusses the applications of biomaterials, including orthopedic, cardiovascular, ophthalmic, and dental applications. The article describes four major categories of biomaterials such as metals, polymers, glass and ceramics, and composites. A discussion on natural materials, nanomaterials, and stem cells is also provided. The article concludes with examples of biomaterials applications, such as endovascular devices, knee implants, and neurostimulation.
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005679
EISBN: 978-1-62708-198-6
...</xref>) Table 1 List of ISO Standards for Biological Evaluation of Medical Devices ( Ref 1 ) Reference Title ISO 10993-1 Guidance on selection of tests ISO 10993-2 Animal welfare requirements ISO 10993-3 Test for genotoxicity, carcinogenicity, and reproductive toxicity ISO 10993-4...
Series: ASM Handbook
Volume: 9
Publisher: ASM International
Published: 01 December 2004
DOI: 10.31399/asm.hb.v09.a0005650
EISBN: 978-1-62708-177-1
... with chemicals. Many of these chemicals used in metallography can cause serious damage on contact. It is best to assume that all chemicals are toxic and that all vapors or fumes will be toxic if inhaled or will be damaging to the eyes. A hood will prevent the working area from being contaminated with these fumes...
Abstract
This article describes the safety precautions required for using laboratory equipment. It reviews the various personal protective equipment specified on the Material Safety Data Sheets (MSDS) for laboratory chemicals and products. The article provides information on the storage and handling of etchants, solvents, acids, bases, and other chemicals. It describes the safety precautions and procedures for handling concentrated and dilute hydrofluoric acid. The article concludes with a discussion on the precautions to be followed in the event of spills and cleanup.
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005667
EISBN: 978-1-62708-198-6
... have the potential to leach out of the polymer and could cause toxicity to the local tissue or even systemically. Biocompatibility of Polymers A major concern for using any polymer in a medical device context is how the body's biological system will react to the presence of that particular...
Abstract
This article discusses several aspects of biocompatibility of polymers, including the selection of a suitable polymer, specific use of a material, contact of polymer on body site, and duration of the contact. It describes the factors influencing the biological response of the polymer from a biocompatibility perspective. These include raw materials, the manufacturing process, cleaning and sterilization processes, and biodegradation and biostability. The article reviews the general testing methods of polymers, such as chemical, mechanical and thermal. It concludes with a section on the guidance, provided by the regulatory authorities, on the biocompatibility testing of polymers and polymer-containing devices that can aid in selecting the right analysis.
Series: ASM Handbook
Volume: 5B
Publisher: ASM International
Published: 30 September 2015
DOI: 10.31399/asm.hb.v05b.a0006030
EISBN: 978-1-62708-172-6
... and residences where family members, especially children, can also be exposed. Because of the sheer number of possible hazardous constituents in industrial coatings, this article can provide only a brief overview of this topic. This overview includes the toxic effects of selected coatings constituents...
Abstract
This article discusses the occupational health hazards related to industrial protective coating application and removal. It explains the health hazards associated with coating constituents such as lead, cadmium, chromium, arsenic, silica, and asbestos. The article also discusses hazard evaluation, hazard controls, Occupational Safety and Health Administration standards, and industry consensus standards. It concludes with a description of containment systems to prevent environmental exposures from industrial paint removal projects.
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005686
EISBN: 978-1-62708-198-6
... detailed information exists, the characterization program may be conducted partially or solely as a paper exercise. In the absence of such details, appropriate analytical techniques must be applied to a material to yield compositional data. Sufficient information must be obtained to identify all toxic...
Abstract
This article provides a background to the biological evaluation of medical devices. It discusses what the ISO 10993 standards require for polymeric biomaterials and presents examples of qualitative and quantitative tests that can be used to satisfy these requirements. The article describes infrared (IR) and thermal analyses that are used extensively to fingerprint polymeric materials. It also presents a discussion on the chemical characterization and risk assessment of extracts. Background information on risk assessments of extracts is also included. The four basic steps that are commonly used in the risk assessment process are discussed. These include hazard identification, dose-response assessment, and exposure assessment, and risk characterization.
Series: ASM Handbook
Volume: 20
Publisher: ASM International
Published: 01 January 1997
DOI: 10.31399/asm.hb.v20.a0002438
EISBN: 978-1-62708-194-8
... and Community Right to Know Act, 1986 (EPCRA), Also known as Superfund Amendments and Reauthorization Act (SARA) Section 313 of Title III of this act includes the Toxics Release Inventory (TRI), which makes hazardous waste and toxins a matter of public record. This act sets fines for violations. Pollution...
Abstract
This article discusses Allenby's two streams for environmental aspects of design: generic and specific concerns. Generic concerns include guidelines that provide the structure in which specific techniques can be developed and used. Specific methods are environmentally responsible for design and specific information that engineers can use. These methods include life cycle assessment, environmental impact assessment, quality function deployment, design for “X”, failure modes and effects analysis, and design for disassembly.
Book Chapter
Series: ASM Handbook
Volume: 4B
Publisher: ASM International
Published: 30 September 2014
DOI: 10.31399/asm.hb.v04b.a0005944
EISBN: 978-1-62708-166-5
... to 927 °C (650 to 1700 °F). Below 343 °C, the lead is too “mushy” ( Ref 3 ). Molten lead is used for patenting of steel wire and for austempering. Due to the toxicity and disposal problems with lead, it is seldom used in the thermal processing of steel. However, because lead possesses a high thermal...
Abstract
The use of gases or molten salts as the quenchant for steel parts is commonly limited to the quenching of high-alloy steel or the carbonizing quenching of low-alloy steel. This article reviews the quenching process of steels with molten metals (quenchant) such as molten lead, molten bismuth, and molten sodium. It also contains tables that list the physical properties of lead, bismuth, sodium, and molten sodium.
Book Chapter
Series: ASM Desk Editions
Publisher: ASM International
Published: 01 November 1995
DOI: 10.31399/asm.hb.emde.a0003012
EISBN: 978-1-62708-200-6
... to recommended loadings of about 1% for less toxic additives ( Ref 1 ). Antimicrobial additives are considered pesticides in the United States ( Ref 1 ). They must be registered for specific applications with the Environmental Protection Agency. Antioxidants As their name suggests, antioxidants...
Abstract
Additives for plastics and elastomers are used to increase the ease of processing and to improve the properties of the final product. Additives improve processing characteristics by increasing lubricity and by stabilizing the polymer. Additives that improve properties include those that decrease static charge development and microbial activity and those that improve flame retardation characteristics, color, light stability, impact resistance, density and mechanical properties. This article focuses on the additives for polymers and elastomers that are used for improving processing--blowing agents, mold-release agents, lubricants, plasticizers, and heat stabilizers--and for improving properties antimicrobials, antioxidants, antistatic agents, colorants, fillers and fiber reinforcements, flame retardants, impact modifiers, light stabilizers, plasticizers, and heat stabilizers. Furthermore, it discusses the method for addition of these additives and the problems faced during compounding.
Book: Surface Engineering
Series: ASM Handbook
Volume: 5
Publisher: ASM International
Published: 01 January 1994
DOI: 10.31399/asm.hb.v05.a0001321
EISBN: 978-1-62708-170-2
...) Exhibits a hazardous characteristic (flammability, corrosivity, reactivity, or toxicity) Is a mixture of solid waste with hazardous waste. The resultant mixture is hazardous with some exceptions. These criteria are summarized in Fig. 3 . As with all environmental regulations, a variety...
Abstract
This article describes selected U.S. environmental statutes and regulations that are pertinent to material surface finishers. It provides information on the applicability, requirements, and permitting conditions of the Clean Air Act, the Resources Conservation and Recovery Act, the Superfund Amendments and Reauthorization Act, and the Clean Water Act.