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in vivo corrosion

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Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005674
EISBN: 978-1-62708-198-6
... biomedical implant alloys are listed in a tabular form. The article presents an overview of surface-modification methods for titanium and its alloys implants. It concludes with a section on biocompatibility and in vivo corrosion of titanium alloys. artificial heart pumps biocompatibility biomaterials...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005654
EISBN: 978-1-62708-198-6
... Abstract This article describes some of the mechanical/ electrochemical phenomena related to the in vivo degradation of metals used for biomedical applications. It discusses the properties and failure of these materials as they relate to stress-corrosion cracking (SCC) and corrosion fatigue (CF...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005665
EISBN: 978-1-62708-198-6
... Abstract This article highlights corrosion resistance and ion release from main transition metallic bearings that are used as medical devices. It discusses the main issues associated with the in vivo presence of ions and their biocompatibility during the exposure of patients to different...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005668
EISBN: 978-1-62708-198-6
... important to test at this value in the laboratory. Dissolved salts, particularly chlorides, are probably the most influential components for implant corrosion in vivo , although by no means the only ones. The internal body electrolyte has the equivalent of 0.9% NaCl in solution. Gases dissolved in body...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005678
EISBN: 978-1-62708-198-6
... hip joint simulators and knee joint simulators, to evaluate the performance of engineering tribological components in machine simulators. The article describes in vivo assessment of total joint replacement performance. ceramics friction hip joint simulators in vivo assessment knee joint...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005682
EISBN: 978-1-62708-198-6
... different types of tissue responses to the biomaterial. The article discusses the testing of implant failure, such as in vitro and in vivo assessment of tissue compatibility. biomaterials biomedical devices cardiovascular applications ceramic implants dental applications functionally-graded hip...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005652
EISBN: 978-1-62708-198-6
... Abstract This article discusses the mechanisms of metal and alloy biocompatibility. It provides information on early testing and experience with metals in medical device applications. The article describes the response to severe corrosion of implant and particulate materials. It provides a...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005653
EISBN: 978-1-62708-198-6
... Abstract This article reviews the corrosion interactions between biomedical alloys, in particular iron-base, titanium-base, and cobalt-base alloys, in complex geometries and in applications where there are significant cyclic stresses and potential for wear and fretting motion. It discusses the...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005683
EISBN: 978-1-62708-198-6
... or implants retrieved from human patients. Some of the corrosion measurements can be performed on specimens implanted in living tissues ( in vivo ) of animals, but the purpose is usually research rather than corrosion performance evaluation. An important feature of the corrosion behavior of most...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005680
EISBN: 978-1-62708-198-6
... device manufacturing. The combination of durability, corrosion resistance, and biocompatibility plays an important role during materials selection for medical device applications. Furthermore, their increasingly intricate designs have resulted in the exploitation of the properties of...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005658
EISBN: 978-1-62708-198-6
..., fatigue, and corrosion in medical device design. It reviews the biocompatibility of nitinol based on corrosion behavior. The article describes the general principles, potential pitfalls, and key properties for manufacturing, heat treatment, and processing of nitinol. biocompatibility corrosion...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005657
EISBN: 978-1-62708-198-6
... metallic device. For example, cleaning of explanted Nitinol stents in bleach-containing solutions may have resulted in erroneous findings of in vivo corrosion ( Ref 5 ). Most importantly, adequate precautions must be undertaken to avoid illness or infection during explant handling. Ultrasonic cleaning...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005669
EISBN: 978-1-62708-198-6
... resulted in the substitution of molybdenum for tungsten in the 1930s. This change also proved beneficial for improving corrosion resistance in Cl − -containing environments such as occur in vivo , making practical the use of cobalt loys for long-term (permanent) in vivo placement. Implants made by...
Series: ASM Handbook
Volume: 11
Publisher: ASM International
Published: 15 January 2021
DOI: 10.31399/asm.hb.v11.a0006829
EISBN: 978-1-62708-295-2
... Abstract Fretting is a wear phenomenon that occurs between two mating surfaces; initially, it is adhesive in nature, and vibration or small-amplitude oscillation is an essential causative factor. Fretting generates wear debris, which oxidizes, leading to a corrosion-like morphology. This...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005655
EISBN: 978-1-62708-198-6
...:10 (b) Systemic toxicity test, ISO 10993:11 Subacute and subchronic toxicity test, ISO 10993:11 Test for pyrogenicity, ISO 10993:11 (c) In vitro alternatives to in vivo tests: (a) EPISKIN Skin Corrosivity Method. (b) Hen's egg test-chorioallantoic membrane, or HET-CAM, test...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005656
EISBN: 978-1-62708-198-6
... withstand physiologic load and support bone ingrowth under this stress ( Ref 90 ). In addition, tantalum has been shown to be corrosion resistant and relatively inert. Tantalum has also been demonstrated to be bioactive in vivo by mode of a bonelike apatite layer formation in simulated body fluid. There...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005675
EISBN: 978-1-62708-198-6
... surface area can provide a focus for corrosion of the implant and loss of metal ions into the tissues. This can be mediated by using a bioactive ceramic material such as hydroxylapatite (HA) as a coating on the porous metal. The fraction of large porosity in any material also degrades the strength of the...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005667
EISBN: 978-1-62708-198-6
... consist of chemical, in vitro (in glass) and in vivo (in life) experiments. For testing the biocompatibility of a polymer, the latter tests use healthy animal models to observe any adverse effects. However, for the eventual medical device, additional testing may be required that uses a disease model...
Book Chapter

By Sam Nasser
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005684
EISBN: 978-1-62708-198-6
... tantalum is used primarily in precision electronic components such as capacitors and high-power resistors, electrodes for use in corrosive environments, and in the lining of reaction vessels. In alloyed form, tantalum is added to steel and other metals to raise their melting points and increase ductility...
Series: ASM Handbook
Volume: 23
Publisher: ASM International
Published: 01 June 2012
DOI: 10.31399/asm.hb.v23.a0005666
EISBN: 978-1-62708-198-6
... (not ions). Particulate debris (and ions) is produced through one of two mechanisms: wear or corrosion. However, the vast majority of implant debris is released in the form of particles ( Ref 3 , Ref 4 , Ref 5 , Ref 6 , Ref 7 ). In fact, of all the factors attempted to be correlated with implant...