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high-throughput drug screening

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Series: ASM Handbook
Volume: 23A
Publisher: ASM International
Published: 12 September 2022
DOI: 10.31399/asm.hb.v23A.a0006892
EISBN: 978-1-62708-392-8
... Abstract Microvalve jetting, with its advantages of low cost, ease of operation, high printing speed, and ability to process living cells with high viability, has been primarily used for fabricating high-throughput drug-screening models, in vitro cellular structures for fundamental cell biology...
Image
Published: 12 September 2022
Fig. 4 High-throughput production via microvalve jetting of alginate-embedded multicellular spheroids for cancer drug screening. Source: Ref 15 . Creative Commons License (CC BY-NC-ND 4.0), https://creativecommons.org/licenses/by-nc-nd/4.0/ More
Series: ASM Handbook
Volume: 23A
Publisher: ASM International
Published: 12 September 2022
DOI: 10.31399/asm.hb.v23A.a0006858
EISBN: 978-1-62708-392-8
..., and tissue formation. Successful in vitro conditioning of the desired cell types plays a key role in achieving the final vascularized tissue, metastatic models, multicellular tissues, or scaffolds for high-throughput drug screening. Figure 1 depicts the overall process flow involved in the majority...
Series: ASM Handbook
Volume: 23A
Publisher: ASM International
Published: 12 September 2022
DOI: 10.31399/asm.hb.v23A.a0006900
EISBN: 978-1-62708-392-8
... (>100 μm) Requires drying step after printing Potential risks with material flow-rate control Parts can be fabricated in a single plane. Binder jet Large material range Near-ambient temperature process Part porosity can be tuned. Potential for high throughput and continuous...
Series: ASM Handbook
Volume: 24A
Publisher: ASM International
Published: 30 June 2023
DOI: 10.31399/asm.hb.v24A.a0007021
EISBN: 978-1-62708-439-0
... method of metal powder production for AM. Gas atomization is preferred for AM feedstock because the powder is spherical with a good packing density and a reproducible, consistent particle size distribution (PSD). It enables large batch sizes with relatively high throughput. The PSD ranges are typically...
Series: ASM Handbook
Volume: 23A
Publisher: ASM International
Published: 12 September 2022
DOI: 10.31399/asm.hb.v23A.a0006855
EISBN: 978-1-62708-392-8
... and lung-cancer-associated fibroblasts were encapsulated into the hydrogel, and spheroid formation by the involved cells was observed. This system represents a suitable model for high-throughput drug-screening studies in tumor-therapy research ( Ref 39 ). Ivanovska et al. ( Ref 67 ) compared...
Series: ASM Handbook
Volume: 23A
Publisher: ASM International
Published: 12 September 2022
DOI: 10.31399/asm.hb.v23A.9781627083928
EISBN: 978-1-62708-392-8
Series: ASM Handbook
Volume: 23A
Publisher: ASM International
Published: 12 September 2022
DOI: 10.31399/asm.hb.v23A.a0006862
EISBN: 978-1-62708-392-8
... ) Vascular stents ( Ref 7 – 9 ) Surgical plates for jaw reconstruction ( Ref 10 ) Drug-delivery devices ( Ref 11 – 13 ) Personal protective equipment ( Ref 14 – 17 ) Furthermore, advancements in AM technologies have led to the fabrication of three-dimensional (3D)-printed tissues and organs...
Series: ASM Handbook
Volume: 23A
Publisher: ASM International
Published: 12 September 2022
DOI: 10.31399/asm.hb.v23A.a0006860
EISBN: 978-1-62708-392-8
... to print single-cell patterns and 2D and 3D biological constructs. Such biological patterns and constructs have been used for various fields of interest related to cell and tissue dynamics, stem cell differentiation and development, and drug screening, to name a few. Single-Cell Printing...
Book Chapter

Series: ASM Desk Editions
Publisher: ASM International
Published: 01 November 1995
DOI: 10.31399/asm.hb.emde.a0003065
EISBN: 978-1-62708-200-6
... from “in-place procedures.” The high volume of inexpensive, more common glass products produced by these processes is usually made from soda-lime silicate glass compositions. These melting and forming processes provide a wide range of possibilities with respect to product quality and cost. Special...
Series: ASM Handbook
Volume: 23A
Publisher: ASM International
Published: 12 September 2022
DOI: 10.31399/asm.hb.v23A.a0006893
EISBN: 978-1-62708-392-8
... bioprinting finds applications in soft/hard tissue engineering, regenerative medicine, tissue/organ transplantation, and clinical research high-throughput screening in pharmaceutical and cancer research. According to different droplet-forming principles, droplet-based bioprinting can be divided into inkjet...
Series: ASM Handbook
Volume: 24
Publisher: ASM International
Published: 15 June 2020
DOI: 10.31399/asm.hb.v24.a0006565
EISBN: 978-1-62708-290-7
... required is on the order of an individual voxel, LIFT based on LDT is required. The application of LIFT for the printing of high-viscosity (100,000 cP) silver nanopastes developed for screen printing applications results in the transfer of voxels exhibiting sharp edges that resemble lithographically...
Series: ASM Handbook
Volume: 10
Publisher: ASM International
Published: 15 December 2019
DOI: 10.31399/asm.hb.v10.9781627082136
EISBN: 978-1-62708-213-6
Series: ASM Handbook Archive
Volume: 10
Publisher: ASM International
Published: 01 January 1986
DOI: 10.31399/asm.hb.v10.9781627081788
EISBN: 978-1-62708-178-8
Series: ASM Handbook
Volume: 24A
Publisher: ASM International
Published: 30 June 2023
DOI: 10.31399/asm.hb.v24A.9781627084390
EISBN: 978-1-62708-439-0
Series: ASM Handbook
Volume: 24
Publisher: ASM International
Published: 15 June 2020
DOI: 10.31399/asm.hb.v24.9781627082907
EISBN: 978-1-62708-290-7