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Additive Manufacturing in Medicine and Craniofacial Applications of 3D Printing
Available to PurchaseSeries: ASM Handbook
Volume: 23A
Publisher: ASM International
Published: 12 September 2022
DOI: 10.31399/asm.hb.v23A.a0006852
EISBN: 978-1-62708-392-8
... Abstract This article provides highlights of the general process and workflow of creating a 3D-printed model from a medical image and discusses the applications of additively manufactured materials. It provides a brief background on Food and Drug Administration (FDA) classification...
Abstract
This article provides highlights of the general process and workflow of creating a 3D-printed model from a medical image and discusses the applications of additively manufactured materials. It provides a brief background on Food and Drug Administration (FDA) classification and regulation of medical devices, with an emphasis on 3D-printed devices. Then, the article discusses two broad applications of 3D printing in craniofacial surgery: surgery and education. Next, it discusses, with respect to surgical applications, preoperative planning, use in the operating room, surgical guides, and implants. The article includes sections on education that focus on the use of 3D-printed surgical simulators and other tools to teach medical students and residents. It briefly touches on the FDA regulations associated with the respective application of 3D printing in medicine. Lastly, the article briefly discusses the state of medical billing and reimbursement for this service.
Series: ASM Handbook
Volume: 23A
Publisher: ASM International
Published: 12 September 2022
DOI: 10.31399/asm.hb.v23A.a0006900
EISBN: 978-1-62708-392-8
... Abstract The application of three-dimensional printers can be revolutionary as a tool for the customization and personalization of pharmaceutical dosage forms. The areas of 3D printing applicable to pharmaceutical manufacturing can be segregated into three categories: extrusion technologies...
Abstract
The application of three-dimensional printers can be revolutionary as a tool for the customization and personalization of pharmaceutical dosage forms. The areas of 3D printing applicable to pharmaceutical manufacturing can be segregated into three categories: extrusion technologies, powder-bed fusion, and stereolithography. Common extrusion-based technologies are fused deposition modeling and pressure-assisted microsyringe; powder-bed fusion is separated by binder jet and selective laser sintering. The synergies between pharmaceutical, or active pharmaceutical ingredient (API), and polymer printing are discussed in this article, with particular attention to how the incorporation of small-molecule APIs changes the material selection, design considerations, processing parameters, and challenges associated with each technology.
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Examples of collagen 3D printing. Gross images of bioinks 3D printed throug...
Available to Purchase
in Three-Dimensional Bioprinting of Naturally Derived Protein-Based Biopolymers
> Additive Manufacturing in Biomedical Applications
Published: 12 September 2022
Fig. 3 Examples of collagen 3D printing. Gross images of bioinks 3D printed through automated gel aspiration-ejection, where different structural shapes, such as cylindrical, quadrangular, and tubular, can be produced. Source: Ref 20 . Reprinted with permission from Wiley
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Examples of silk 3D printing. 3D surface morphology of silk scaffold inkjet...
Available to Purchase
in Three-Dimensional Bioprinting of Naturally Derived Protein-Based Biopolymers
> Additive Manufacturing in Biomedical Applications
Published: 12 September 2022
Fig. 5 Examples of silk 3D printing. 3D surface morphology of silk scaffold inkjet fabricated from (a) 0.5 and (b) 1 mg/mL solutions. Reprinted with permission from Ref 99 . Copyright © 2014 American Chemical Society
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Published: 01 January 2005
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in Developments and Trends in Additively Manufactured Medical Devices
> Additive Manufacturing in Biomedical Applications
Published: 12 September 2022
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(a) Interim crown design (b) fabricated via PolyJet 3D printing. Source: Re...
Available to Purchase
in Developments and Trends in Additively Manufactured Medical Devices
> Additive Manufacturing in Biomedical Applications
Published: 12 September 2022
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(a) Fabricating a skull model by 3D printing. CT, computed tomography. (b) ...
Available to Purchase
in Developments and Trends in Additively Manufactured Medical Devices
> Additive Manufacturing in Biomedical Applications
Published: 12 September 2022
Fig. 16 (a) Fabricating a skull model by 3D printing. CT, computed tomography. (b) Fabricating a brain model by 3D printing and silicone casting techniques. MRI, magnetic resonance imaging. (c) Fabricating a vascular model with blisterlike dilation bulges by 3D printing and coating techniques
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Published: 12 September 2022
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Polymer powder 3D-printing processes using laser fusion/sintering. PBF-LB/P...
Available to PurchasePublished: 12 September 2022
Fig. 1 Polymer powder 3D-printing processes using laser fusion/sintering. PBF-LB/P, laser-based powder-bed fusion of polymers; TPBF, thermal powder-bed fusion
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Schematic illustrations for jetting technologies of 3D printing. (a) Inkjet...
Available to PurchasePublished: 12 September 2022
Fig. 1 Schematic illustrations for jetting technologies of 3D printing. (a) Inkjet printing. (b) Microvalve jetting. (c) Laser-assisted jetting
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Summary of the main 3D printing approaches. (a) Thermal inkjet printers ele...
Available to Purchase
in Three-Dimensional Bioprinting of Naturally Derived Protein-Based Biopolymers
> Additive Manufacturing in Biomedical Applications
Published: 12 September 2022
Fig. 1 Summary of the main 3D printing approaches. (a) Thermal inkjet printers electrically heat the printhead to produce air-pressure pulses that force droplets from the nozzle. Piezoelectric inkjet printers apply an electric current to the printhead, forcing the ink onto a substrate. (b
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Percent usage of 3D printing technologies to manufacture anatomical models ...
Available to PurchasePublished: 12 September 2022
Fig. 6 Percent usage of 3D printing technologies to manufacture anatomical models at the point of care at Mayo Clinic over an examination of 180 days
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Merging 3D printing and sculpting techniques to create realistic and accura...
Available to PurchasePublished: 12 September 2022
Fig. 11 Merging 3D printing and sculpting techniques to create realistic and accurate anatomical models. (a) A neck anastomosis training model was created using both fabrication methods (3D printing and sculpture). (b) Exploded view of the training model indicates the level of complexity
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Surgical navigation of a pelvic tumor. Design and 3D printing of patient-sp...
Available to PurchasePublished: 12 September 2022
Fig. 1 Surgical navigation of a pelvic tumor. Design and 3D printing of patient-specific instruments. (a) 3D, digital model. (b) Products (3D-printed biomodel, navigation instruments). (c) Product utility. (d) Actual procedure. Source: Ref 51
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Various 3D printing techniques to manufacture biomedical sensors. (a) Polyj...
Available to Purchase
in Additively Manufactured Biomedical Energy Harvesters
> Additive Manufacturing in Biomedical Applications
Published: 12 September 2022
Fig. 7 Various 3D printing techniques to manufacture biomedical sensors. (a) Polyjet method. UV, ultraviolet. (b) 3D inkjet system. (c) Laser sintering technique. (d) Stereolithography system. (e) Fused deposition modeling. (f) Digital light processing. Source: Ref 119 . Creative Commons
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Piezoresistive sensor fabrication and 3D printing of nanocomposite ink. DCM...
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in Additively Manufactured Biomedical Energy Harvesters
> Additive Manufacturing in Biomedical Applications
Published: 12 September 2022
Fig. 8 Piezoresistive sensor fabrication and 3D printing of nanocomposite ink. DCM, dichloromethane; FSE, flexible/stretchable element. Source: Ref 121 . Creative Commons License (CC BY 4.0), https://creativecommons.org/licenses/by/4.0/
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Piezocapacitive-based 3D-printed pressure sensor. (a) Inkjet printing metho...
Available to Purchase
in Additively Manufactured Biomedical Energy Harvesters
> Additive Manufacturing in Biomedical Applications
Published: 12 September 2022
Fig. 9 Piezocapacitive-based 3D-printed pressure sensor. (a) Inkjet printing method using polydimethylsiloxane (PDMS) microstructures on polyethylene terephthalate substrate. (b) Capacitance changes with a range of applicable pressure. ITO, indium tin oxide. Reproduced from Ref 123
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Progression of 3D-printed dental prostheses from 3D-printed framework on le...
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in Material Aspects of Additively Manufactured Medical Devices
> Additive Manufacturing in Biomedical Applications
Published: 12 September 2022
Fig. 2 Progression of 3D-printed dental prostheses from 3D-printed framework on left to polished part and finally veneered finished product. Image courtesy of EOS North America
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Fixation simulation on a 3D-printed acetabular model. (a) 3D-printed, patie...
Available to PurchasePublished: 12 September 2022
Fig. 2 Fixation simulation on a 3D-printed acetabular model. (a) 3D-printed, patient-specific plate model. (b) 3D-printed acetabular model. (c) Match test of the 3D-printed, patient-specific plate and 3D-printed acetabular model. (d) Simulation of all 3.5 mm (0.14 in.) screw insertions (arrow
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