This article summarizes the general fatigue and fracture properties of cast steels, namely, toughness, fatigue, and component design factors such as section size and discontinuities. It describes the various factors that influence fatigue of cast steels. These factors include section size, defect size, stress modes, and waveform types. The article discusses various fracture mechanics in cast steels: cyclic stress-strain behavior and low- and high-cycle fatigue life behavior; plane-stress fracture toughness; plane-strain fracture toughness; constant-amplitude fatigue crack initiation and growth; and variable-amplitude fatigue crack initiation and growth.