This article provides an overview of fatigue and fracture resistance of aluminum alloys. It discusses the characteristics of aluminum alloy classes and the fracture mechanics of aluminum alloys. The article tabulates relative stress-corrosion cracking ratings for high-strength wrought aluminum products. It analyzes the selection of various alloys for stress-corrosion cracking resistance, including aluminum-lithium alloys, copper-free 7XXX alloys, and casting alloys. The article presents a list of typical tensile properties and fatigue limit of aluminum alloys. It also describes the effects of composition, microstructure, thermal treatments, and processing in fatigue crack growth of aluminum alloys.